Investigating whether topical application of a non toxic molecule improves epidermal pH and barrier function in atopic dermatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN97515110

Enrollment

Registered

2010-10-21

Start date

2008-09-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Skin

Interventions

1. Intervention: Gel containing a naturally-occuring chemical onto the skin of one their forearms every day for 6 weeks 2. Control: On the other forearm they will be asked to apply the same cream/gel

Eligibility

Inclusion criteria

Inclusion criteria: Not provided at time of registration

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Secondary

Measure	Time frame
1. General skin condition using a well established scoring system for AD (SCORAD) 2. Skin barrier function transepidermal water loss (TEWL), measured at monthly intervals	—

Primary

Measure	Time frame
Each week volunteers will be asked to complete a short questionnaire (POEM)	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026