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Non-invasive brain stimulation for dysphagia after acute stroke

Randomised controlled dose response trial of transcranial direct current stimulation for dysphagia after acute stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN97286108
Enrollment
45
Registered
2015-04-02
Start date
2015-04-01
Completion date
Unknown
Last updated
2017-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Stroke

Interventions

Dose response of transcranial direct current stimulation

Sponsors

University of Manchester
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All patients with dysphagia following acute anterior or posterior cerebral circulation stroke that present dysphagia for the first time, within the first weeks from symptoms and up to 6 weeks post stroke. The presence of dysphagia will be based on the results of screening procedures by the research team. Patients will be always recruited after 48-72 hours post lesion 2. There is no age limit 3. Patients must be medically stable 4. Lesions have to be verified on imaging techniques, either magnetic resonance (MR) scan or computerised tomography (CT), information which will be collected

Exclusion criteria

Exclusion criteria: 1. Advanced dementia 2. Other neurological conditions that may explain swallowing difficulty (dysphagia) 3. Previous history of dysphagia 4. Presence of cardiac pacemaker of implanted cardiac defibrillator 5. Any metal in the head or eyes 6. Use of medication which decreases seizure threshold 7. A diagnosis other than stroke is suspected (e.g. brain tumour) 8. Any severe concomitant chronic medical condition that compromises cardiac or respiratory status, 9. Significant structural abnormalities of the mouth or throat 10. Patients requiring oxygen treatment will be excluded at point of entry to prevent further compromise to already impaired respiratory system 11. Patients may be reconsidered for recruitment if they are successfully weaned off oxygen treatment

Design outcomes

Primary

MeasureTime frame
Changes in safety of swallowing based on formal assessments

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026