Postpartum haemorrhage Pregnancy and Childbirth Postpartum haemorrhage
Conditions
Interventions
Treatment groups: 200 mcg or 400 mcg or 600 mcg sublingual misoprostol given once immediately post partum.
Control group: 10 IU IM oxytocin.
Observation of intrauterine pressure and vital sign for 1
Sponsors
University of Liverpool (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women who have had spontaneous vaginal delivery 2. Women with gestational age >34 weeks 3. Women who give an informed written consent 4. Aged = 18 years
Exclusion criteria
Exclusion criteria: 1. Women with history of Postpartum Haemorrhage (PPH) 2. Women with history of Antepartum Haemorrhage (APH) 3. Women with previous caesarean section 4. Women with 5 or more previous deliveries at over 28 weeks 5. Women who have Premature Rupture of Membranes (PROM) 6. Women with anaemia (Hb 4.0 Kgs 8. Women who have induced or augmented labour with any uterotonic drugs 9. Women with multiple pregnancies 10. Women with polyhydraminos 11. Women with pre eclampsia 12. Women with infection 13. Women who do not give a written consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montevideo units (MVU) (contractions over 10 minutes) for intrauterine pressure values over the first 15 minutes after placental delivery (Baby delivery) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. MVU at 30, 60, 90 and 120 minutes 2. Pulse, blood pressure, and temperature at 30, 60, 90 and 120 minutes 3. Blood loss, measured in the 120 minutes after delivery | — |
Countries
Libya
Outcome results
None listed