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Preconception care and gestational diabetes prevention in Bangladesh

Preconception care and its effect on the prevention of gestational diabetes in Bangladesh

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN97130017
Enrollment
800
Registered
2023-08-23
Start date
2023-08-20
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of preconception care on prevention of gestational diabetes Pregnancy and Childbirth

Interventions

Participants will be allocated at random in a 1:1 ratio to an intensive lifestyle intervention to promote increased physical activity and dietary modification or to only standard care to the control g
(2) total fat intake <30% of the energy consumed
(3) saturated fat intake <10% of the energy consumed
(4) carbohydrate intake 50–60% of the energy consumed
and (5) fiber intake 20–30 g/day. Based on each participant’s current status of body weight, and physical activity, along with food and nutrient intakes which have been assessed from the baseline surv

Sponsors

Non-Communicable Disease Control Program of Directorate General of Health Services, Ministry of Health and Family Welfare, Government of the People's Republic of Bangladesh
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Women aged 18-40 years and planning pregnancy within 6 months to 1 year. 2. Permanent residents. 3. Willing to participate and be available for the whole period of the study.

Exclusion criteria

Exclusion criteria: 1. Known case of T2DM, prediabetes 2. Previous history of GDM. 3. Women diagnosed with any physical or mental illness at the time of screening.

Design outcomes

Primary

MeasureTime frame
Gestational diabetes (GDM) will be identified according to the IADPSG (International Association of Diabetes and Pregnancy Study) criteria using an oral glucose tolerance test at the first antennal visit, 24-48 weeks (if find normal at ANC visit), and 32-36 weeks (if find normal at 24-28 weeks).

Secondary

MeasureTime frame
1. Diabetes and prediabetes will be identified according to WHO criteria using an oral glucose tolerance test (including fasting and 2h 75-gram oral glucose test) at the time of registration, 6 weeks after delivery, and 1 year after delivery. 2. HbA1c by using the HPLC method, fasting lipid profile (including total cholesterol, triglycerides, HDL-C, and LDL-C), urine RME, will be at registration, first antennal visit, 6 weeks after delivery, and 1 year after delivery. 3. Hb% and blood grouping will be measured at registration, and an ultrasonogram (USG) will be done at the first antennal visit. 4. Anthropometric measurements including height, weight, hip, and waist circumference (WC) will be taken at registration, first antennal visit, 6 weeks after delivery, and 1 year after delivery.

Countries

Bangladesh

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026