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Feasibility study of the Clear Water Protocol in acute stroke

A feasibility study of the implementation of the Clear Water Protocol for stroke survIvors with dysphagia in acute stroke unit setting (RAPIDS)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN96981732
Enrollment
100
Registered
2026-01-13
Start date
2024-12-02
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Circulatory System

Interventions

There are four stages of the research project. Stage 1: Developmental work to inform national stakeholder co-design workshops The preparatory work will combine quantitative and qualitative methods and

Sponsors

Sheffield Teaching Hospitals NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients with acute stroke (ischaemic or haemorrhagic) who: 1. Are a patient on the Acute Stroke Unit, Royal Hallamshire, Sheffield Teaching Hospitals NHS Foundation Trust (STHFT). 2. Have had a clinical bedside swallowing evaluation by a Speech and Language Therapist (SLT) or equivalent trained health professional and who are considered at risk of aspiration with thin liquids (Level 0 Thin Fluids). 3. Have been on their swallowing recommendations (thickened fluids or NBM) for 72 hours. 4. Have extreme impulsivity or excessive coughing will have water under supervision. 5. Can sit out in a chair (minimum mobility hoist to chair). 6. Can engage with eating (even if they require assistance). 7. Can give written consent in English, Urdu or Arabic to enter the study or consultee of the patient either a family member or the medical team who gives written consent for the patient to participate on their behalf. 8. Are over 18 years of age.

Exclusion criteria

Exclusion criteria: Patients with acute stroke (ischaemic or haemorrhagic) who: 1. Have a pre-existing dysphagia and are recommended to drink thickened fluids pre-stroke. 2. Are fully dependent for feeding. 3. Have an active pneumonia, acute exacerbation of Chronic Obstructive Pulmonary Disease or active asthma with symptoms. 4. Have a degenerative neurological condition (e.g., Parkinson’s Disease, Multiple Sclerosis). 5. Have severe kidney disease (CKD 4/ requiring dialysis). 6. Are enrolled in other intervention studies related to dysphagia. 7. Experience extreme coughing to the point of discomfort with thin fluids. 8. Have severe oral stage dysphagia such that the majority of the water bolus is lost anteriorly. 9. Have an oral or dental infection, including lesions associated with head and neck cancer treatment. 10. Have an absent pharyngeal swallow response. 11. Are for imminent discharge i.e. within the next 7 days or for palliation.

Countries

England, United Kingdom

Contacts

Public ContactSarah Wilkinson
sarah.wilkinson71@nhs.net+44 (0)114 271 1658 ext 11658

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026