Suicidal ideation, self-harm and suiciadal behaviour in patients with autism-spectrum disorder Mental and Behavioural Disorders
Conditions
Interventions
The study design is a multicentre single-blind randomized controlled trial with two arms. The experimental arm is Dialectical Behaviour Therapy and the active control arm is individual psychotherapy.
Sponsors
VU University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 65 years 2. Meets DSM V criteria for autism spectrum disorder 3. Suicidal ideation above cutoff on SIDAS (score =21) and/or level of suicidality/self-harming behavior on the LPC rated as severe (score = 2 on any item) 4. Outpatient status
Exclusion criteria
Exclusion criteria: 1. IQ <80 2. Addiction to illicit drugs in need of clinical detoxification 3. Insufficient mastery of the Dutch language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Suicidal ideation measured by the 'Suicidal Ideation Attributes Scale' and self-harm and suicidal behaviour as measured by the 'Lifetime Parasuicide Count'. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Social Anxiety (Social Interaction Anxiety Scale) 2. Depression (Beck Depression Inventory-2) 3. Quality of Life (Manchester Short Assessment of Quality of Life) 4. Social functioning (Personal and Social Performance Scale) 5. Autism symptoms (Autism Spectrum Quotient-28 & Social Responsiveness Scale) 6. Emotion Regulation {Difficulties in Emotion Regulation Scale: mediator) 7. Working Alliance (Working Alliance Questionnaire: mediator) 8. Alexithymia (Toronto Alexithymia Scale: moderator) 9. Utilities (EuroQoL-5D: cost-utilities) 10. Health costs (Trimbos/iMTA questionnaire for costs associated with Psychiatric illness: cost utilities) | — |
Countries
Netherlands
Outcome results
None listed