Intensive care, critically ill patients Nutritional, Metabolic, Endocrine hypocaloric diet with intensive insulin therapy
Conditions
Interventions
All patients admitted to ICU are screened for eligibility. Once patient is eligible for study, informed consent is obtained from the next of kin. The patient is then randomized to one of the following
Sponsors
King Abdulaziz City for Science and Technology (KACST) (Saudi Arabia)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients receiving nasogastric tube feeding 2. Aged >18 years 3. Staying >48 hours in Intensive Care Unit (ICU)
Exclusion criteria
Exclusion criteria: 1. Refused consent 2. Terminal illness 3. DNR (Do Not Recussitate; no code, no escalation) in first 48 hours of admission 4. Enteral feeding cannot be started within 48 hours 5. Total Parentral Nutrition (TPN) 6. Oral feeding 7. Liver transplant 8. Seizures within last 6 months 9. Expected to stay less than 48 hours 10. Age less than 17 years 11. Readmission 12. Brain dead within 48 hours 13. Pregnancy 14. Post cardiac arrest 15. Enrolled in another study 16. Hypoglycemic coma 17. Blood glucose less than 6.1mmol in first 48 hours 18. Type 1 diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU, 28 day and Hospital mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. ICU length of stay 2. Duration of mechanical ventilation 3. Incidence of nosocomial infections | — |
Countries
Saudi Arabia
Outcome results
None listed