Cardiopulmonary exercise testing and stress echocardiography as screening methods to detect pulmonary hypertension in patients with connective tissue diseases (CTD)

Cardiopulmonary exercise testing and stress echocardiography as screening methods to detect pulmonary hypertension in patients with connective tissue diseases (CTD): an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN96212539

Enrollment

100

Registered

2009-02-27

Start date

2009-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary hypertension in patients with connective tissue diseases (CTD) Musculoskeletal Diseases Other systemic involvement of connective tissue

Interventions

Patients affected by different forms of CDT will be included in the study. All patients will undergo CPET as well as stress echocardiography to detect secondary PH. Based on general disease characteri

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults >=18 years, both males and females 2. Patients with all forms of CTD

Exclusion criteria

Exclusion criteria: 1. Contraindications for CPET according to current guidelines 2. Congestive heart failure 3. Coronary heart disease 4. Myocardial infarction within the last 6 months 5. Pulomonary diseases other than CTD 6. Primary myopathy

Design outcomes

Primary

Measure	Time frame
Exercise capacity	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026