Effects of yogurt containing probiotics on salivary Streptococcus mutans and Lactobacillus sp. counts in children

Effects of yogurt containing probiotics on salivary Streptococcus mutans and Lactobacillus sp. counts in Colombian children aged from 6 to 12 years: a randomised controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN96117208

Enrollment

Registered

2018-03-20

Start date

2017-07-16

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy children not being under antibiotic therapy the two previous months to the start of the intervention Not Applicable

Interventions

The children were randomised by block randomisation into group A (intervention arm: ‘Original’ probiotics yogurt containing Lactobacillus casei and Lactobacillus acidophilus) or group B (placebo contr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy children 2. Both genders 3. Age 6-12 years old 4. Lactose tolerant

Exclusion criteria

Exclusion criteria: 1. Dry mouth or xerostomy 2. Morbid obesity 3. Antibiotic therapy

Design outcomes

Primary

Measure	Time frame
Streptococcus mutans and Lactobacillus sp. Colony Forming Units (CFU) counts; microbiological examinations performed at baseline and at the end of the intervention period	—

Secondary

Measure	Time frame
Salivary pH measured using a calibrated digital pH-meter and buffering capacity at baseline and at the end of the intervention period	—

Countries

Colombia

Contacts

Public ContactJose Pieruccini

josepieruccini@ustabuca.edu.co+57 (0)3017850598

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026