Chronic neurological or neuromuscular disorder Nervous System Diseases Neurological or neuromuscular disorder
Conditions
Interventions
There will be two groups in the study:
1. An immediate exercise intervention group
2. A waiting list control group who will receive the exercise intervention after a wait of three months
Thus all pa
Sponsors
Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All individuals with: 1. A diagnosis of a chronic neurological or neuromuscular disorder 2. Aged sixteen years and over 3. No cognitive, sensory or psychological impairments precluding full engagement with training and experimental paradigm 4. Able to participate for the study period 5. Able to stand and walk 10 metres using any aid or assistance
Exclusion criteria
Exclusion criteria: All individuals: 1. Unable to meet the inclusion criteria, or those unwilling or unable to undertake the programme 2. With additional impairments (e.g. orthopaedic) restricting mobility or any contraindications to exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure will be the Physical Activity questionnaire in the Elderly (PASE), which is a participant and carer completed measure of activity and community mobility. This will be measured at 0, 3 and 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary measures will be measured at 0, 3 and 6 months, and will include: 1. Physical activity participation as measured by the number of sessions attended. The number will be determined from the computerised attendance data at the IFI centres and attendance diaries kept by the trainer 2. Home mobility step counts measured by accelerometer readings over an 8-day period 3. Community activity level will be measured with a long term ambulatory activity monitor that will be worn on the leg for 8 days (full 168 hour week and only removed for bathing). This method of ambulatory monitoring provides essential information relating to the actual level of activity (and hence a good measure of functional ability) as measured by step counts and time spent sitting or lying compared to walking 4. Isometric muscle strength (lower limb: hip flexors, extensors, abductors, quadriceps, hamstrings, ankle dorsiflexors and plantarflexors; upper limb: biceps and triceps) and hand grip. Muscle testing will be carried out in standardised validated manner and include three isometric contractions with a wall mounted myometer (MIE Medical Instruments, UK) for each muscle group or dynamometer (handgrip) (MIE Medical Instruments, UK) 5. Leg power and speed will be recorded using a 'leg power meter' (Medical Laboratory Workshops, Nottingham) 6. The General Health Status questionnaire (36-item short form health survey [SF-36]) and quality of life measure (Euro-Quality of life instrument [EQ-5D]) 7. Weight (kg) 8. Barthel Index 9. The Fatigue Severity Scale (FSS) 10. Falls' questionnaire for neurological and neuromuscular populations 11. 2 minute and 10 metre mobility test. During walking tests movement profiles (cadence and step times) will be evaluated by a triaxial accelerometer 12. Fitness test (modified Sjostrand incremental test) - 2 minute initial unweighted cycle and then 1 minute incremental increases in resistance until paticipants wish to stop. During exercise, expired air, heart ra | — |
Countries
United Kingdom
Outcome results
None listed