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A study of how workers with occupational asthma breathe out forcefully and quickly (peak expiratory flow)

Analyses of existing peak expiratory flow in workers with occupational asthma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN95990788
Enrollment
250
Registered
2023-05-31
Start date
2023-06-01
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occupational asthma Respiratory

Interventions

Trial Objectives 1. To determine whether different exposures at work cause different patterns of peak flow response 2. To determine whether exposure to supposed irritants differ from supposed sensiti

Sponsors

University Hospitals Birmingham NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Records from all workers with possible occupational asthma who have kept frequent measurements of their breathing using peak flow meters over several weeks at work and at home as part of their investigation to confirm their diagnosis and who have at least one positive score for occupational asthma, will be identified from the Oasys database on NHS trust computers (derived from- and part of the electronic patient record) from 1990 to the present day

Exclusion criteria

Exclusion criteria: 1. Patients for whom PEF records were inadequate for analysis (eg. too few readings, insufficient number of days at work) 2. Records of patients whose occupational exposures are unknown

Design outcomes

Primary

MeasureTime frame
The ABC score from the Oasys program for the PEF study measured using patient records

Secondary

MeasureTime frame
Measured using patient records at a single time point: 1. Differences in the pattern of reaction (immediate, flat, late) 2. Recovery time (1,2, >2 days) 3. Diurnal variation in PEF home vs work 4. Sensitivity and specificity of questionnaire responses (for the questionnaire analysis)

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026