Using dynamic 4D-CT imaging to measure the blood flow in the arteries and muscles to evaluate wounds in diabetic feet

Combined evaluation of blood flow and tissue perfusion in diabetic feet by contrast-enhanced 4D-CT imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN95737449

Enrollment

Registered

2023-03-14

Start date

2021-01-01

Completion date

Unknown

Last updated

2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assessment of critical limb ischemia in patients with diabetes Circulatory System

Interventions

Patients with diabetic foot and a high suspicion of critical limb ischemia (CLI) receive a diagnostic IADSA examination as part of their vascular workup at the diabetic foot clinic. In addition, the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Diabetic foot 2. Suspicion of critical limb ischemia 3. Referred for IADSA

Exclusion criteria

Exclusion criteria: 1. Known allergic reactions to iodinated contrast agents 2. Hyperthyroidism 3. Dialysis

Design outcomes

Primary

Measure	Time frame
Arterial blood flow and tissue perfusion are quantified voxel-wise from 4D-CT data using 2mL of contrast agent at a single time point	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026