Liver transplantation Injury, Occupational Diseases, Poisoning Failure and rejection of transplanted organs and tissues
Conditions
Interventions
A prospective, randomised, single-center study. Patients of the treatment group received 1 ng/kg body weight /min iloprost (BayerVital AG Berlin, Germany), systemically administered for 7 days post-li
Sponsors
University Hospital of Jena (Universitätsklinikum Jena) (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years, either gender 2. Full size orthotop liver transplantation
Exclusion criteria
Exclusion criteria: 1. Circulatory instability 2. Noradrenaline doses >0.5 µg/kg body weight/min 3. Pregnancy 4. Known intolerance of iloprost
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of primary graft dysfunction within 48 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Rate of re-transplantation caused by initial graft non-function within 48 hours postoperatively 2. Time of hospitalisation (duration of follow-up depends on the circumstances of each patient) 3. Length of stay in intensive care unit (duration of follow-up depends on the circumstances of each patient) 4. Rate of complications due to biliary tract lesions within 1-year follow-up | — |
Countries
Germany
Outcome results
None listed