Randomised Controlled Trial of 6% Cellulose Sulfate (CF) Gel and the Effect on Vaginal Human Immunodeficiency Virus (HIV) Transmission

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95638385

Enrollment

2574

Registered

2005-07-08

Start date

2005-06-13

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV infection Infections and Infestations Human immunodeficiency virus (HIV)

Interventions

Randomized to 6% CS gel or Placebo gel

both arms receive condoms and safer sex counseling. Any curable sexually transmitted infection (STI) or urinary tract infection (UTI) will be treated. Referrals for other conditions. Three monthly gy

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Healthy women at risk of HIV infection through their own sexual behavior.

Exclusion criteria

Exclusion criteria: HIV positive women or at risk of HIV through other transmission routes; pregnant women.

Design outcomes

Primary

Measure	Time frame
HIV infection (incident)	—

Secondary

Measure	Time frame
NG infection; CT infection	—

Countries

Benin, Burkina Faso, India, South Africa, Uganda

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 5, 2026