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Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass graft (CABG): a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN95608630
Enrollment
20
Registered
2005-08-26
Start date
2003-09-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery bypass graft Circulatory System Coronary artery bypass graft

Interventions

Strict glucose control (blood glucose between 80-110 mg/dl) versus placebo (blood glucose >200 mg/dl).

Sponsors

Radboud University Nijmegen Medical Centre (The Netherlands)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adults, after uncomplicated CABG 2. Non-diabetics

Exclusion criteria

Exclusion criteria: 1. Diabetes 2. Renal failure 3. Use of anti-inflammatory drugs 4. Recent myocardial ischemia

Design outcomes

Primary

MeasureTime frame
Cytokine levels—

Secondary

MeasureTime frame
Complement concentration—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 4, 2026