Thrombocytopenia Haematological Disorders Thrombocytopenia
Conditions
Interventions
There will be no additional hospital appointments or venepunctures done specifically for this research. During a routine hospital appointment, each participant will be given patient information and th
Sponsors
University of Bristol
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age range >16 years old 2. Male and female 3. Low platelet count AND need for treatment 4. Hb>100g/l
Exclusion criteria
Exclusion criteria: 1. Hb<100g/L 2. Patients unable to consent (e.g. due to mental incapacity)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Candidate biomarkers of clinical response are assessed by evaluating the correlation of laboratory assay results to clinical response data (bleeding and platelet count data over at least 12 months, the latter will be collected from routine blood tests done on patients according to clinical need). | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and negative predictive value of some assays to specific causes of low platelet count and discrepancy of results from different types of assay used to measure low platelet counts. | — |
Countries
United Kingdom
Outcome results
None listed