Microwave endometrial ablation without endometrial preparation in the outpatient setting

The effects of hormonal endometrial preparation before microwave endometrial ablation: patient acceptability, treatment outcomes and costs - a single centre unblinded randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95516133

Enrollment

210

Registered

2009-11-25

Start date

2001-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menorrhagia Urological and Genital Diseases Excessive, frequent and irregular menstruation

Interventions

Trial arm one: microwave endometrial ablation (MEA) 4 weeks after endometrial preparation with danazol or GnRH analogue in theatre setting Trial arm two: MEA out-patient setting 5 to 7 days after star

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women aged 30 to 55 years 2. Suitable for endometrial ablation as treatment for heavy periods 3. Premenopausal 4. Not planning to have any (further) children

Exclusion criteria

Exclusion criteria: 1. Unsuitable for endometrial ablation 2. Unwilling to have procedure under local anaesthetic 3. Allergic to local anaesthetic agents

Design outcomes

Primary

Measure	Time frame
Patient acceptability	—

Secondary

Measure	Time frame
Measured immediately-post procedure and at 1 year and 5 years: 1. Menstrual outcomes 2. Quality of life 3. Costs	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026