Obesity Nutritional, Metabolic, Endocrine Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male gender (Differences in estrogen concentrations between men and woman result in greater reliance on fat oxidation during exercise in woman. Between the different phases of the female menstrual cycle substrate utilization also varies) 2. Body-Mass-Index >25 and 18 and <50 years 4. Verbal and written information of the participants, signed declaration of consent 5. No cardiovascular risk [completion of the Physical Activity Readiness Questionnaire (PAR-Q)]
Exclusion criteria
Exclusion criteria: 1. Female gender 2. Cardiac insufficiency > New York Heart Association (NYHA) 1 3. Continuous arrhythmia 4. Respiratory obstruction 5. High blood pressure (> 140/90mmHg) 6. Body-Mass-Index 34,99 kg/m2 7. Age 50 years 8. Any medication 9. Signed declaration of consent missing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. ANP 2. Respiratory exchange rate (RER). The RER specifies the ratio of carbon dioxide (CO2) eliminated to oxygen (O2) consumed. The RER depends on the metabolic substrate used for generating energy. Using stoichiometric equations, the RER can be applied to determine the amounts of carbohydrates and fatty acids metabolized. Energy production can also be reliably estimated in the same manner. 3. The rating of perceived exertion (RPE). The RPE method requires that a person subjectively rates how difficult the work is, using a numerical scale that is related to exercise intensity. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Free fatty acids 2. Lactate 3. Catecholamines (adrenaline, noradrenaline, dopamine) 4. Growth hormone (GH) 5. Insulin 6. Glycerol All of which indicate changes in the metabolic process. | — |
Countries
Switzerland