Influence of the suturing technique on the wound healing of the palate after obtaining a connective tissue graft

Influence of suturing technique and postoperative palatal flap thickness on wound healing and patient morbidity after connective tissue harvesting. A randomized controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95407036

Enrollment

Registered

2018-02-15

Start date

2015-10-21

Completion date

Unknown

Last updated

2018-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatal healing Ear, Nose and Throat Palatal healing

Interventions

Using a computerized randomisation method, participants are allocated to one of two groups. Group 1: Participants receive a continuous interlocking suture used in the donor site Group 2: Participants

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Men and women over 18 years old 2. Showing Miller Class I,II or III (Miller 1985) single gingival recession

Exclusion criteria

Exclusion criteria: 1. Any systemic conditions that might impact directly on the systemic inflammatory status (e.g.autoimmune diseases) 2. Severe cognitive or psychiatric disorders 3. Chronic immunosuppressant therapy 4. Lactating females and current pregnancy 5. Patients with coagulation disorders excluded from the trial 6. Smokers who consume more than 10 cigarettes per day 7. Patients using partial or full denture, which has any contact with the palate

Design outcomes

Primary

Measure	Time frame
Association between suture technique and early healing index is measured one week after surgery and after suture removal, the early-wound healing index (EHI) using five different degrees: 1. Complete flap closure without fibrin line at the palate 2. Complete flap closure with fibrin line at the palate 3. Complete flap closure with small fibrin clot(s) at the palate 4. Incomplete flap closure with partial necrosis of the palatal tissue 5. Incomplete flap closure with complete necrosis of the palatal tissue (more than 50 % of the former flap is involved)	—

Measure

Time frame

Association between suture technique and early healing index is measured one week after surgery and after suture removal, the early-wound healing index (EHI) using five different degrees: 1. Complete flap closure without fibrin line at the palate 2. Complete flap closure with fibrin line at the palate 3. Complete flap closure with small fibrin clot(s) at the palate 4. Incomplete flap closure with partial necrosis of the palatal tissue 5. Incomplete flap closure with complete necrosis of the palatal tissue (more than 50 % of the former flap is involved)

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Secondary

Measure	Time frame
1. Association between preoperative palatal thickness and early healing is measured one week after surgery using a early-wound healing index (EHI) (Fickl et al. 2014) and the preoperative measurement taken with the endodontic file and light curing flowable composite 2. Association between postoperative palatal flap thickness and early healing is measured one week after surgery using a early-wound healing index (EHI) (Fickl et al. 2014) and the postoperative measurement taken with the endodontic file and light curing flowable composite 3. Pain Perception of the patients was determined with VAS pain values daily until 8 weeks after surgery	—

Measure

Time frame

1. Association between preoperative palatal thickness and early healing is measured one week after surgery using a early-wound healing index (EHI) (Fickl et al. 2014) and the preoperative measurement taken with the endodontic file and light curing flowable composite 2. Association between postoperative palatal flap thickness and early healing is measured one week after surgery using a early-wound healing index (EHI) (Fickl et al. 2014) and the postoperative measurement taken with the endodontic file and light curing flowable composite 3. Pain Perception of the patients was determined with VAS pain values daily until 8 weeks after surgery

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Countries

Spain

Contacts

Public ContactGiovanni Maino

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026