Comparison of mesh fixation techniques in open ventral hernia repair

A randomized clinical trial comparing two different mesh fixation techniques in open retromuscular ventral hernia repair

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95370808

Enrollment

Registered

2021-10-09

Start date

2021-05-06

Completion date

Unknown

Last updated

2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retromuscular ventral hernia repair Surgery

Interventions

Adults with ventral hernias will be included in this study and they will undergo open ventral hernia repair with retromuscular placement of the mesh. The two techniques that will be applied will be e

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults 2. Ventral hernia 3. Eligible for hernia repair

Exclusion criteria

Exclusion criteria: Serious health problems that prevent a safe surgical intervention, for example serious heart or kidney failure

Design outcomes

Primary

Measure	Time frame
Postoperative pain measured using the visual analogue scale of pain 0-10 at 3 and 6 months	—

Secondary

Measure	Time frame
1. Postoperative pain measured using the visual analogue scale of pain 0-10 at 7, 14, 30 days and 12 months 2. Hernia recurrence measured by clinical examination, CT scan if necessary at 7, 14, 30 days and 12 months 3. Other complications measured by clinical examination, laboratory and radiological tests if necessary at 7, 14, 30 days and 12 months 4. Duration of surgery in minutes, measured after the end of the operation 5. Length of hospital stay in days, measured after the patient’s discharge 6. The amount and the type of analgesic drugs needed at 7, 14, 30 days and 3, 6 and 12 months 7. Quality of life measured using HerQLes and EuraHS QOL preoperatively and at 3, 6 and 12 months. These questionnaires assess the impact of abdominal hernia and surgery on rehabilitation, mental health, daily activities, work, exercise, pain, aesthetic outcome, and sex life.	—

Measure

Time frame

1. Postoperative pain measured using the visual analogue scale of pain 0-10 at 7, 14, 30 days and 12 months 2. Hernia recurrence measured by clinical examination, CT scan if necessary at 7, 14, 30 days and 12 months 3. Other complications measured by clinical examination, laboratory and radiological tests if necessary at 7, 14, 30 days and 12 months 4. Duration of surgery in minutes, measured after the end of the operation 5. Length of hospital stay in days, measured after the patient’s discharge 6. The amount and the type of analgesic drugs needed at 7, 14, 30 days and 3, 6 and 12 months 7. Quality of life measured using HerQLes and EuraHS QOL preoperatively and at 3, 6 and 12 months. These questionnaires assess the impact of abdominal hernia and surgery on rehabilitation, mental health, daily activities, work, exercise, pain, aesthetic outcome, and sex life.

—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026