Achilles Tendinopathy Management: platelet-rich plasma versus eccentric loading programme

Achilles Tendinopathy Management: a randomised controlled trial comparing platelet-rich plasma with an eccentric loading programme

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95369715

Enrollment

Registered

2010-02-18

Start date

2010-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achilles tendinopathy Musculoskeletal Diseases Enthesopathies of lower limb, excluding foot

Interventions

Intervention: Platelet Rich Plasma Injection. The procedure will involve taking 52 ml of whole blood combined with 8 ml of an anti-coagulant which will be immediately centrifuged at 2400 for 12 minut

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Midsubstance achilles tendinopathy diagnosed clinically through pain on palpation at a level of 2 - 6 cm above the tendon insertion and ultrasonography 2. The tendinopathy will be causing pain during loading activities and limit those activities 3. Duration of at least 3 months 4. Aged over 18 years, either sex

Exclusion criteria

Exclusion criteria: 1. Tendinopathies secondary to systemic conditions such as rheumatoid arthritis and diabetes 2. Insertional Achilles tendinopathies 3. Pregnancy 4. Previous Achilles rupture or surgery 5. Dislocation or fracture of the lower limb within the preceeding 12 months

Design outcomes

Primary

Measure	Time frame
VISA-A at 6, 12, 24, 30, 36 and 52 weeks	—

Secondary

Measure	Time frame
EQ-5D and complications at 6, 12, 24, 30, 36 and 52 weeks	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026