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Reducing stigma and promoting HIV wellness/mental health of sexual and gender minorities: a novel group-based cognitive behavioural therapy program in Nigeria

Evaluation of an internalized stigma reduction intervention for men who have sex with men, and transgender women, in Lagos, Nigeria via a prospective delayed group randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN95309635
Enrollment
300
Registered
2024-02-23
Start date
2022-04-26
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of mental health disorders (depression, anxiety) and increased uptake of HIV prevention and treatment services Mental and Behavioural Disorders

Interventions

After recruitment, from separate listings of MSM and transgender women (TGW) enrolled participants, an investigator used a random numbers table and assigned individuals from each list to an interventi
there were separate groups for MSM or TGW (given different experiences and social networks). Within 10 days of completion of the baseline survey, research assistants called participants to inform them

Sponsors

Population Council
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. 18 years or older 2. Assigned male at birth 3. [Among MSM subgroup] Had sex with a biological man in the last year; [Among Transgender women subgroup] Identify as a woman 4. Willing to participate in all four sessions of the intervention 5. Willing to participate in the study 6. Residing in Lagos State for the next 1 year

Exclusion criteria

Exclusion criteria: 1. Do not agree to participate in either the group sessions or study surveys 2. Planning to move out of Lagos State within the next one year 3. Currently participating in any other stigma reduction intervention 4. Not providing consent to participate in the intervention and study 5. Not providing contact information for follow-up

Design outcomes

Primary

MeasureTime frame
Internalized stigma related to being a sexual/gender minority and living with HIV (among those individuals living with HIV), measured using an adaptation of the Internalized AIDS-Related Stigma Scale (IA-RSS) at baseline and three additional points (approximately 1 month after baseline, 2 months after baseline, and 3 months after baseline)

Secondary

MeasureTime frame
Measured at baseline and three additional points (approximately 1 month after baseline, 2 months after baseline, and 3 months after baseline): 1. Depression measured using the Patient Health Questionnaire-8 (PHQ-8) 2. Anxiety measured using the General Anxiety Disorder-7 (GAD-7), such as ‘trouble relaxing’ and ‘not being able to control or stop worrying’ in the last 2 weeks 3. Coping was measured using the 4-item Brief Coping Scale 4. Uptake of pre-exposure prophylaxis and antiretroviral therapy (among participants living with HIV). Among those with HIV, adherence was defined as reporting “No days” to the question “During the past 3 days, on how many days have you missed all your pills?”. Antiretroviral treatment self-efficacy was assessed based on seven items from a validated scale (HIV-Adherence Self-Efficacy Scale with last month as the reference period.

Countries

Nigeria

Contacts

Public ContactWaimar Tun
wtun@popcouncil.org+1 (0)2409450638

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 11, 2026