Electronically delivered, multi-component intervention to reduce unnecessary antibiotic prescribing in primary care

Conditions

Antibiotic prescribing/respiratory tract infections Infections and Infestations

Martin Gulliford, Dorota Juszczyk, A Toby Prevost, Jamie Soames, Lisa McDermott et al. (14 authors)

Health Technology Assessment2019-03-0139 citations

Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial

Martin Gulliford, A Toby Prevost, Judith Charlton, Dorota Juszczyk, Jamie Soames et al. (14 authors)

BMJ2019-02-12120 citations

10.1136/bmj.l236

Electronically delivered, multicomponent intervention to reduce unnecessary antibiotic prescribing for respiratory infections in primary care: a cluster randomised trial using electronic health records—REDUCE Trial study original protocol

Dorota Juszczyk, Judith Charlton, Lisa McDermott, Jamie Soames, Kirin Sultana et al. (13 authors)

BMJ Open2016-08-0116 citations

10.1136/bmjopen-2015-010892

Interventions

There will be two trial arms. 1. The control trial arm practices will continue with usual clinical care. 2. Practices in the Intervention trial arm will receive complex

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: General practices will be included in the trial if: 1. They presently contribute up-to-standard data to CPRD 2. Consent to participation in the trial 3. Are located in areas that have given research governance approval for the study Data for non-trial CPRD practices will be eligible for observational data analysis to gauge the representativeness of practices and patients participating in the trial. Data for individual participants will be included if they are currently registered with CPRD general practices

Exclusion criteria

Exclusion criteria: No other exclusion criteria

Design outcomes

Primary

Measure	Time frame
Number of antibiotic prescriptions for RTI per 1,000 registered patient years at 12 months follow-up	—

Secondary

Measure	Time frame
1. Number of consultations for RTI with antibiotic prescribed / Total RTI consultations (%) at 12 months follow-up 2. Consultations and prescriptions as defined above during 14 days after the index consultation at 12 months follow-up 3. Number of consultations for RTI per 1,000 registered patient years 12 months follow-up 4. All antibiotic prescriptions per 1,000 registered patient years at 12 months follow-up 5. Number of hospital admission (by category) per 1,000 registered patient years at 12 months follow-up 6. Estimated costs of all health care utilisation per 1,000 registered patient years at 12 months follow-up 7. Broad categories of RTI subgroups including colds, sore throat, cough and bronchitis, otitis media and rhino-sinusitis (NICE, 2008) at 12 months follow-up 8. Number of adverse events ((peritonsillar abscess, mastoiditis, skin infections and bacterial infections) (by category) per 1,000 registered patient years over at 12-months follow-up	—

Measure

Time frame

1. Number of consultations for RTI with antibiotic prescribed / Total RTI consultations (%) at 12 months follow-up 2. Consultations and prescriptions as defined above during 14 days after the index consultation at 12 months follow-up 3. Number of consultations for RTI per 1,000 registered patient years 12 months follow-up 4. All antibiotic prescriptions per 1,000 registered patient years at 12 months follow-up 5. Number of hospital admission (by category) per 1,000 registered patient years at 12 months follow-up 6. Estimated costs of all health care utilisation per 1,000 registered patient years at 12 months follow-up 7. Broad categories of RTI subgroups including colds, sore throat, cough and bronchitis, otitis media and rhino-sinusitis (NICE, 2008) at 12 months follow-up 8. Number of adverse events ((peritonsillar abscess, mastoiditis, skin infections and bacterial infections) (by category) per 1,000 registered patient years over at 12-months follow-up

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Countries

United Kingdom

Outcome results

None listed