Primary cough headache Signs and Symptoms
Conditions
Interventions
The study consists of one visit. Previously, a pre-screening questionnaire performed at the cough clinic will determine potential eligibility. Study visit: consent will be sought and, after screening,
Sponsors
King's College London
King’s College Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients are capable of giving signed informed consent indicating that the subject has been informed of all pertinent aspects of the trial detailed in the patient information sheet (PIS), informed consent form (ICF), and in the protocol 2. Subjects must be willing to receive a telephone call or travel to and from King’s College Hospital as preferred, during normal working hours 3. Diagnosis of Primary Cough Headache (PCH) using criteria previously published 4. Aged 18-80 years inclusive 5. Willing and able to comply with scheduled visits and study procedures
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding from consent until the end of study involvement 2. History of psychosis, depression or psychological diseases either (a) requiring ongoing psychoactive drugs, or (b) that the Investigator has reason to believe will either affect the patient’s neural pathways or hinder the performance of the patient with regard to ability to successfully complete the tasks required of them according to the protocol 3. History/presence of cerebral haemorrhage, brain tumour, brain aneurysm, cryptococosis or other brain mass lesion within the last 12 months 4. Any other medical condition that in the opinion of the Investigator would make the subject unsuitable for the study 5. Inclusion to another research study within the past 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical features and prevalence of cough headache in patients attending a Cough Unit and the differences between primary and secondary cough headache, measured using questionnaire adapted from the usual headache clinic and cough clinic interviews at the single study visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured using questionnaire adapted from the usual headache clinic and cough clinic interviews at the single study visit: 1. Specific comorbidities related to cough headache 2. The use of opioids and other drugs in cough patients and possible relationship with the development of chronic headache 3. The utility of the modified Valsalva manoeuvre in these patients | — |
Countries
United Kingdom
Contacts
Public ContactDavid Moreno Ajona
Outcome results
None listed