Intraoperative fluid optimisation using stroke volume variation in high risk surgical patients

Intraoperative fluid optimisation using stroke volume variation in high risk surgical patients: a randomised prospective single-centre study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95085011

Enrollment

120

Registered

2009-10-29

Start date

2007-07-01

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid optimisation of high risk surgical patients undergoing major abdominal surgery Surgery Abdominal

Interventions

Patients were randomised into protocol or control group using sealed envelopes method. Fluid management in control group patients was managed using routine cardiovascular and clinical

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: High risk surgical patients of both gender scheduled for intraabdominal surgery with presumed blood loss of more than 1,000 ml or longer than 120 minutes with open peritoneal cavity.

Exclusion criteria

Exclusion criteria: 1. Patients aged less than 18 years 2. Patients with irregular heart rhythm 3. Those with body weight less than 55 kg or more than 140 kg

Design outcomes

Primary

Measure	Time frame
Postoperative morbidity based on occurrence (rate and number) of postoperative infectious and organ complications until 30 days after operation.	—

Secondary

Measure	Time frame
1. Duration of hospital and intensive care unit (ICU) stay 2. All cause mortality 3. Biochemical parameters of oxygen debt during operation and in early postoperative period (8 hours)	—

Countries

Czech Republic

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 31, 2026