Feasibility of exercises to treat swallowing difficulty after cancer surgery to remove the voice box

An investigation of the feasibility of exercises as a swallowing difficulty treatment after laryngectomy compared with standard treatment (no intervention) as measured on patient self-report outcome measures and instrumental dysphagia evaluation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95066540

Enrollment

Registered

2023-07-21

Start date

2023-09-01

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Swallowing function after laryngectomy Signs and Symptoms

Interventions

This is a feasibility study with two work packages. A feasibility study design has been chosen as there is limited research in this area. Undertaking a feasibility study allows the researcher to find

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Person with laryngectomy with self reported swallowing difficulty or diet restriction 2. Person with laryngectomy between 18 and 100 years

Exclusion criteria

Exclusion criteria: 1. Person with laryngectomy more than 3 months post surgery or completion of oncological treatment 2. Person with laryngectomy with documented cognitive impairment

Design outcomes

Primary

Measure	Time frame
Pressure measurements during swallow measured using High-Resolution Manometry at baseline and 3 months	—

Secondary

Measure	Time frame
1. Number of repeat swallows measured using the 100 ml water swallow test at baseline, and 3, 6 and 18 months 2. Patient report of swallow score measured using the MD Anderson Dysphagia Inventory at baseline, and 3, 6 and 18 months 3. Pharyngeal constriction ratio measurement measured using a videofluoroscopy swallow evaluation at baseline and 3 months 4. Clinician report of diet level score measured using a Functional Oral Intake Scale Timepoints at baseline, and 3, 6 and 18 months 5. Neck range of motion score measured using a goniometer at baseline, and 3, 6 and 18 months 6. Cost-effectiveness measured using the EuroQol EQ-5D-5L health-related quality of life measure at baseline, and 3, 6 and 18 months	—

Measure

Time frame

1. Number of repeat swallows measured using the 100 ml water swallow test at baseline, and 3, 6 and 18 months 2. Patient report of swallow score measured using the MD Anderson Dysphagia Inventory at baseline, and 3, 6 and 18 months 3. Pharyngeal constriction ratio measurement measured using a videofluoroscopy swallow evaluation at baseline and 3 months 4. Clinician report of diet level score measured using a Functional Oral Intake Scale Timepoints at baseline, and 3, 6 and 18 months 5. Neck range of motion score measured using a goniometer at baseline, and 3, 6 and 18 months 6. Cost-effectiveness measured using the EuroQol EQ-5D-5L health-related quality of life measure at baseline, and 3, 6 and 18 months

—

Countries

England, United Kingdom

Contacts

Public ContactMargaret Coffey

margaret.coffey10@imperial.ac.uk+44 (0)203 311 1761

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026