Cold Pulsatile Perfusion in Asystolic donor Renal Transplantation

A multicentre randomised controlled study of cold Pulsatile Perfusion in Asystolic donor Renal Transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN95022818

Enrollment

205

Registered

2005-05-10

Start date

2006-08-18

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney preservation prior to transplantation Surgery Kidney transplantation

Interventions

Machine perfusion of the kidney before transplantation versus simple cold storage

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects (aged 18 years and over, either gender) undergoing transplantation of a kidney from a non-heart-beating (asystolic) cadaver organ donor.

Exclusion criteria

Exclusion criteria: Added 24/02/2009: 1. Lack of informed consent 2. Positive cross-match 3. Previous recipient of non-renal transplant

Design outcomes

Primary

Measure	Time frame
1. Incidence of delayed graft function (need for dialysis in the first 7 days) 2. Calculated glomerular filtration rate (GFR) (MDRD technique) at 7 days	—

Secondary

Measure	Time frame
1. Patient survival 2. Graft survival 3. Renal function measured using calculated GFR 4. Never function rate 5. Time to last dialysis post transplant 6. Acute rejection incidence 7. Cost comparison at one and five years	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026