Colonic resection above the peritoneal reflection Digestive System Colonic resection above the peritoneal reflection
Conditions
Interventions
Targeted-volume application guided by esophageal doppler vs conventional volume application
Sponsors
Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Written patient consent 2. Patients who undergo colonic resection above the peritoneal reflection 3. Patients who are treated within the context of an accelerated post-operative recovery program
Exclusion criteria
Exclusion criteria: 1. Accommodation in an institution due to an official or judicial order 2. No written consent from patient 3. Unwillingness to allow storage and sharing of anonymised disease data in the context of the clinical study 4. Simultaneous participation of the patient in another study or having been in a study which was terminated less than one week ago 5. American Society of Anaesthesiologists (ASA) classification >III 6. Advanced disease of the oesophagus of nasopharyngeal cavity 7. Operations in the area of the oesophagus or nasopharynx within the last 3 months 8. Systemic steroid therapy 9. Moderate or severe heart valve disease 10. von Willebrands disease 11. History of bleeding tendency 12. Liver disease (Child B or C cirrhosis, End-Stage Liver Disease [MELD] score >17) 13. Age 2.0 mg/dL) 15. Chronic heart failure New York Heart Association (NYHA) class III or IV 16. History of intracranial haemorrhage 17. Allergy to hydroxy-ethyl starch
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in the amount of intravenously administered crystalloid and colloid fluid on the day of operation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Reduction of the intraoperative requirement for vasoactive drugs 2. Time to hospital discharge 3. Rate of postoperative complications (pain, delirium. infections, cardiac, pulmonary, gastrointestinal and renal dysfunction). Patients will be monitored until they fulfill the hospital discharge criteria or up to 30th postoperative day. | — |
Countries
Germany, Netherlands, Norway
Outcome results
None listed