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Equity for suction tamponade access to treat postpartum haemorrhage

Equity for suction tamponade access to treat postpartum haemorrhage: The ESTA project

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN94743923
Enrollment
80
Registered
2025-11-28
Start date
2026-07-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High risk of postpartum haemorrhage Pregnancy and Childbirth

Interventions

The method of randomisation was sequentially numbered, sealed opaque envelopes with allocations in computer-generated random sequence to intervention and routine care. USTAT purpose-designed soft pla

Sponsors

Wits Health Consortium
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 years and older 2. Planned vaginal or caesarean birth 3. One or more risk factors for PPH, including: 3.1. Previous PPH 3.2. Hypertension and pre-eclampsia 3.3. Induction of labour 3.4. Emergency caesarean birth 3.5. Anaemia 3.6. Multiple pregnancy 3.7. Polyhydramnios 3.8. Macrosomia 3.9. Antepartum haemorrhage

Exclusion criteria

Exclusion criteria: Any serious medical conditions

Design outcomes

Primary

MeasureTime frame
Combined frequency of adverse device effects and device deficiencies measured using the number of recorded incidents in patient medical records at birth, up to discharge from hospital

Secondary

MeasureTime frame
Blood loss after birth measured using a gravimetric method (ml) at 30 minutes after birth;Blood loss > 500 ml measured using a gravimetric method (ml) at 1 hour after birth;Blood loss > 1000 ml measured using a gravimetric method (ml) at 1 hour after birth;Efficiency of suction measured using ultrasound assessment of residual blood in the uterus or blood expressed from the uterus after tube removal (ml) at 30 minutes after birth;Blood pressure, pulse and shock index measured using blood pressure measurement (mmHg); beats per minute; beats per minute/mmHg at 15 minutes after vaginal birth or caesarean;Haemoglobin levels measured using an automated haematology analyzer (g/dL) at pre-delivery and post-delivery;Blood transfusion (units) from birth to hospital discharge measured using data collected from patient medical notes at at one time point;ICU admission at birth to hospital discharge measured using data collected from patient medical notes of incidents at at one time point;Death by hospital discharge measured using data collected from patient medical notes of incidents at at one time point;Active bleeding from the uterus continuing for more than 10 minutes (main efficacy outcome) measured using data collected from patient medical notes of incidents at at one time point;Any adverse event from birth till hospital discharge measured using data collected from patient medical notes of incidents at at one time point;Pain experienced (no pain/mild /severe/unbearable) measured using an ordinal scale at after birth;Additional interventions to stop bleeding (e.g. more uterotonics, compressive measures, UBT, laparotomy, hysterectomy) after birth till hospital discharge measured using data collected from patient medical notes of incidents at at one time point;Was USTAT effectively inserted? measured using a question (yes/no/unknown) and nominal data recording at after birth;How easy was it for health care providers to insert the suction tube uterine tamponade (easy/moderately

Countries

South Africa

Contacts

Public ContactG Justus Hofmeyr
justhof@gmail.com+27 83 2809402

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 10, 2026