Intracytoplasmic sperm injection (ICSI) and embryo culture Pregnancy and Childbirth Intracytoplasmic sperm injection (ICSI) and embryo culture
Conditions
Interventions
Participants are randomly allocated to one of two groups.
Group 1: Participants receive intracytoplasmic sperm injection (ICSI) treatments carried out using ISM1 for embryo culture and transfer.
Gro
Sponsors
Gynepro S.R.L.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female patients with at least one previous unsuccessful IVF attempt, in which a clinical pregnancy was not established (including biochemical pregnancies or miscarriages) 2. Aged between 25 and 45
Exclusion criteria
Exclusion criteria: 1. Women older than 45 years old 2. Patients with male partners with testicular spermatozoa or severe oligoastenoteratozoospermia (total sperm number less than 1,000,000 and sperm motility less than 5%)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Implantation rate (defined as the number of implanted embryos per number of transferred embryos) is measured 30 days after embryo transfer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy rate (defined as the number of pregnancies per number of transferred embryos) is measured using ultrasound of gestational chamber 30 days after embryo transfer. | — |
Countries
Italy
Outcome results
None listed