Does intramedullary plugging reduce blood transfusion requirements in total knee replacement?

Does intramedullary plugging reduce blood transfusion requirements in total knee replacement? A randomised controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN94713892

Enrollment

100

Registered

2010-02-09

Start date

2009-12-24

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma and Orthopaedics - total knee replacements Surgery

Interventions

Patients who have total knee arthroplasty will be randomised into two groups. One group will have intramedullary plugging with retransfusion drains and one group will have retransfusion drains only.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Male and female patients 2. Aged 50-90 years 3. Undergoing primary total knee replacement surgery

Exclusion criteria

Exclusion criteria: Patients undergoing unicompartmental knee replacements and revision knee replacements

Design outcomes

Primary

Measure	Time frame
Allogenic blood transfusion requirements	—

Secondary

Measure	Time frame
Post-operative blood loss assessed by: 1. Haemoglobin levels in first 3 days of the post-operative period 2. Total amount of blood collected in drain in the first 24 hours after surgery	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026