Post-Operative Delirium Investigation in the United KingdoM (PODIUM 1)

Modifiable perioperative risk factors for postoperative delirium in older adults undergoing major elective non-cardiac surgery: a feasibility cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN94663125

Enrollment

Registered

2018-02-07

Start date

2017-10-01

Completion date

Unknown

Last updated

2023-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium Mental and Behavioural Disorders Delirium

Interventions

Pre-operatively the participants are assessed for delirium and undergo a series of questionnaires. Presence of postoperative delirium (POD) are assessed on the first four postoperative days. Pre-exist

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients over 65 years of age scheduled to undergo major elective, non-cardiac, non neurosurgical elective surgery. Surgical severity will be decided by reference to SORT (Surgical Outcome Risk Tool) criteria. 2. Patient who lack capacity to consent will be included as long as they have a personal consultee who is willing to discuss the study and offer assent, ideally this will be a close relative

Exclusion criteria

Exclusion criteria: 1. Patients who are 64 years of age and under 2. Those who have require urgent or emergency surgery 3. Those undergoing cardiac and neurosurgery 4. Those unable to provide written informed consent 5. Those unable to understand written English if a translator is not available as part of routine care at the time of recruitment 6. Potential participants that do not have a personal consultee will not be included in the study

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium in patients over 65 years of age following major, elective, non-cardiac surgery in the first four days postoperatively. Screening for delirium will be performed using the 4AT. Additional non study delirium assessments, such as the Confusion assessment method in the intensive care unit (CAM-ICU)25 which may be performed in critical care areas post op, will also be recorded for comparison.	—

Measure

Time frame

Incidence of postoperative delirium in patients over 65 years of age following major, elective, non-cardiac surgery in the first four days postoperatively. Screening for delirium will be performed using the 4AT. Additional non study delirium assessments, such as the Confusion assessment method in the intensive care unit (CAM-ICU)25 which may be performed in critical care areas post op, will also be recorded for comparison.

—

Secondary

Measure	Time frame
1. Number of eligible patients, recruitment rates and retention rates throughout the study. 2. Time required for data collection, preoperative and daily postoperative delirium assessments. 3. To confirm the added value of employing the regional trainee research network (INCARNNET) to deliver the study. Specifically, what proportion of patient consent, data collection and post-operative testing is performed by anaesthesia trainees from this group, especially the success of weekend delirium assessment by trainees	—

Measure

Time frame

1. Number of eligible patients, recruitment rates and retention rates throughout the study. 2. Time required for data collection, preoperative and daily postoperative delirium assessments. 3. To confirm the added value of employing the regional trainee research network (INCARNNET) to deliver the study. Specifically, what proportion of patient consent, data collection and post-operative testing is performed by anaesthesia trainees from this group, especially the success of weekend delirium assessment by trainees

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026