Acute lumbar intervertebral disc herniation Musculoskeletal Diseases herniation
Conditions
Interventions
Patients were randomized to either 1.0 cc Celestone (40 mg/mL) plus 1.0 cc 0.5% bupivicaine (treatment), or 1.0 cc sterile saline plus 1.0 cc 0.5% bupivicaine (control).
Sponsors
WorkSafeBC Research Secretariat (Canada)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 19 years or older 2. Pain in a single lower extremity below the level of the knee of less than 18 week duration 3. Presence of at least one of the following on physical examination - positive straight leg test, motor deficit, or reflex abnormality 4. Presence of a herniated nucleus pulposus (HNP) demonstrated by CT or MRI at a level and side corresponding to symptoms and signs
Exclusion criteria
Exclusion criteria: 1. History of an adverse reaction to local anaesthetic or steroids 2. Any spinal injection within the last 6 months 3. Cauda equina syndrome, progressive neurological deficit, or lower extremity weakness of less than 3/5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. LegPain40: LegPain40 is a 0 to 40 aggregate pain score based on severity of pain/discomfort in the leg (sciatica) over the past week when it was i) most severe, ii) least severe, iii) average, and iv) at present time, with 0 being no pain and 10 being pain as bad as it can be. 2. BackPain10: BackPain10 is a 0 to 10 scale of severity of back pain/discomfort over the past week when it was most severe. 3. Modified Roland-Morris Disability Questionnaire (RDQ): RDQ measures the degree to which a patient?s functional capacity is limited by back pain. The modified RDQ is a 23-item questionnaire developed specifically for patients with sciatica, and has good internal consistency, validity, and responsiveness in this population of patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of progression to surgery | — |
Countries
Canada
Outcome results
None listed