Skip to content

Live music for preterm infants

Musical intervention for extremely preterm infants during NICU stay: a feasibility pilot study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN94562698
Enrollment
40
Registered
2019-01-31
Start date
2019-09-01
Completion date
Unknown
Last updated
2021-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Being born extremely preterm (i.e. <30 weeks gestation) or with very low birth weight (i.e. <1000 grams) Neonatal Diseases

Interventions

After consent, eligible infants will be randomly assigned to one of the two arms, music therapy or care as usual. Assignment to treatment allocation will be done through a web portal. The randomisatio

Sponsors

University Medical Center Groningen
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Born with a gestational age < 30 weeks and/or with a birth weight < 1000 grams 2. Admitted to Neonatal Intensive Care Unit of the University Medical Center Groningen 3. Written informed consent from both parents

Exclusion criteria

Exclusion criteria: Inability of parents to understand and/or speak Dutch

Design outcomes

Primary

MeasureTime frame
Feasibility, defined as 1. Drop-out of children is lower than 20% 2. The sessions are not increasing stress for the child 3. Participant rate of parents is >50% 4. >50% of parents evaluate the intervention as positive 5. >50% of caregivers evaluate the intervention as positive Feasibility will be measured after the study has included 40 infants, but during the study the trialists will closely monitor for overstimulation according to COMFORTneo scores by the music therapist.

Secondary

MeasureTime frame
1. Hemodynamic parameters (i.e. heart rate, respiratory rate, blood pressure and oxygen saturation) measured before, during and after each therapy session 2. Parental stress levels measured using the State and Trait Inventory (STAI) at baseline, after the three weeks of intervention and at discharge 3. Infant stress levels measured using COMFORTneo scores before and after each therapy session 4. Short-term neurological outcome measured using General Movements Assessment at baseline, before and after a therapy session in the second week of therapy, after three weeks of intervention and at three months corrected age

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026