Angiotensin Converting Enzyme (ACE) inhibitors in renal transplant recipients with left ventricular hypertrophy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN94487168

Enrollment

Registered

2007-03-29

Start date

2001-01-01

Completion date

Unknown

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Left ventricular hypertrophy assessed by echocardiography in non diabetic chronic kidney disease patients receiving renal transplant Circulatory System left ventricular hypertrophy

Interventions

Randomization to either ACE inhibitors or no therapy. Conventional antihypertensive therapy allowed in order to achieve blood pressure (BP) nearly 130/80 mmHg

Eligibility

Inclusion criteria

Inclusion criteria: Non diabetic renal transplant recipients with persisting LVH following successful renal transplant

Exclusion criteria

Exclusion criteria: 1. Subjects receiving second or dual transplant 2. Subjects with unstable renal graft function 3. Proteinuria > 1 g/ 24 hr 4. Congestive heart failure 5. Hemodinamically significant artery stenosis

Design outcomes

Primary

Measure	Time frame
Change in left ventricularvmass index at 18 months	—

Secondary

Measure	Time frame
Cardiovascular events during follow-up	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026