Study of the influence of a lung recruitment strategy on oxygenation, lung mechanics and dead-space in thoracic surgery

Alveolar recruitment strategy improves lung function during thoracic surgery: a prospective, randomised study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN94238623

Enrollment

Registered

2011-06-01

Start date

2009-01-07

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic surgery Surgery Thoracic surgery

Interventions

Patients undergoing elective thoracotomy in the lateral position requiring one-lung ventilation and an arterial catheter were randomised to receive: 1. Lung recruitment manoeuvre with an inspiratory p

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Elective adults patients undergoing open thoracic surgery in lateral position requiring one-lung ventilation lasting longer than 40 minutes

Exclusion criteria

Exclusion criteria: Previous contralateral lobectomy, uncompensated cardiac disease, arrhythmias with hemodynamic repercussions, severe air trapping (residual volume > 150%) and presence of large bullae

Design outcomes

Primary

Measure	Time frame
1. Arterial blood gases 2. Volumetric capnography 3. Ventilatory and hemodynamic data These were recorded at the end of each one of the following study periods: 1. TLVbaseline: 5 min after placing the patient in the lateral position during TLV 2. TLV20: 20 min after placing the patient in the lateral position during TLV 3. OLV20: 20 min after OLV ventilation 4. OLV40: 40 min after OLV ventilation 5. TLVend: 10 min after re-establishing TLV once pulmonary resection was completed	—

Measure

Time frame

1. Arterial blood gases 2. Volumetric capnography 3. Ventilatory and hemodynamic data These were recorded at the end of each one of the following study periods: 1. TLVbaseline: 5 min after placing the patient in the lateral position during TLV 2. TLV20: 20 min after placing the patient in the lateral position during TLV 3. OLV20: 20 min after OLV ventilation 4. OLV40: 40 min after OLV ventilation 5. TLVend: 10 min after re-establishing TLV once pulmonary resection was completed

—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026