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The effect of intracameral anesthesia on macular thickness and ganglion cell-inner plexiform layer thickness after uneventful phacoemulsification surgery

The effect of intracameral anesthesia on macular thickness and ganglion cell-inner plexiform layer thickness after uneventful phacoemulsification surgery: Prospective and randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN94155463
Enrollment
100
Registered
2013-09-20
Start date
2013-03-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Senile cataract Eye Diseases Senile cataract

Interventions

Optical coherence tomography imaging was performed before and after the cataract surgery All patients were randomly assigned a number based on a surgical chart: 1. intracameral lidocaine group receiv

Sponsors

Balikesir University (Turkey)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients requiring phacoemulsification surgery for the treatment of senile cataract were included. Inclusion criteria were the presence of senile cataract between 45 and 85 years of age and a clear fundus examination before the surgery.

Exclusion criteria

Exclusion criteria: Exclusion criteria were 1. Pre-existing macular diseases such as macular edema, epiretinal membrane, macular hole and age-related macular degeneration 2. Ocular diseases such as diabetic retinopathy, glaucoma and previous uveitis 3. Pre-existing refractive error: ±3.00 dioptries 4. History of previous intraocular surgery (except cataract surgery in the fellow eye within the previous 6 months) or laser treatment 5. Diabetes, hypertension or other systemic disease that could affect the eye and topical and/or systemic medications with known interference on macular thickness such as steroids and diuretics. 6. Patients with operative complications and eyes with media opacities which could reduce the signal strength and lead to a segmentation error in preoperative measurements were also excluded from the study.

Design outcomes

Primary

MeasureTime frame
Macular thickness analyses with spectral domain optical coherence tomography measured at baseline and at 1 day, 2 days, 1 week, 1 month and 3 months after surgery.

Secondary

MeasureTime frame
Ganglion cell-inner plexiform layer and peripapiller retinal nerve fiber layer thickness analyses as well as visual acuity changes measured at baseline and at 1 day, 2 days, 1 week, 1 month and 3 months after surgery.

Countries

Turkey

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026