Appendicitis in paediatrics Infections and Infestations Acute appendicitis
Conditions
Interventions
1. Interval appendicectomy
2. Planned interval appendicectomy 6-8 weeks following successful non-operative treatment of appendix mass
3. Watchful waiting
4. Regular (3 monthly) observation for a 1 yea
Sponsors
Southampton University Hospitals NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis of acute appendicitis with appendix mass 2. Appendix mass palpable clinically, during examination under anaesthetic or identified radiologically (ultrasound or CT scan) 3. Have been successfully treated nonoperatively during the acute stage of the illness 4. Aged >3yrs and <16 yrs 5. Male or female
Exclusion criteria
Exclusion criteria: 1. Aged less than 3 years or more than 16 years at the time of initial presentation 2. Co-existing gastrointestinal disease e.g. inflammatory bowel disease 3. Presence of major associated abnormalities or immune defect 4. Inability to obtain informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of acute appendicitis within 12 months of recruitment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cost analysis 2. Histology of resected appendix 3. Significant complications during or following interval appendicectomy within 12 months | — |
Countries
United Kingdom
Outcome results
None listed