Levothyroxine and selenium effect on endothelial progenitor cells count in hypothyroid subjects

Levothyroxine and selenium effect on endothelial progenitor cells count in hypothyroid subjects: an interventional single centre trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN93811021

Enrollment

100

Registered

2015-09-05

Start date

2015-05-01

Completion date

Unknown

Last updated

2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endothelial progenitor cells in hypothyroid patients Nutritional, Metabolic, Endocrine

Interventions

The study has four treatment arms: 1. First arm, hypothyroid patients received Levothyroxine (once a day) 2. Second arm hypothyroid patients received Selenium 83 mg (on

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Hypothyroid patients having TSH>4.5mIU/L and <20mIU/L

Exclusion criteria

Exclusion criteria: 1. Cardiovascular disease 2. Diabetes 3. Hypertension 4. Drugs interfering with EPC count

Design outcomes

Primary

Measure	Time frame
EPC count in hypothyroid patients before and three months after treatment	—

Secondary

Measure	Time frame
Anthropometric and biochemical measures before and after treatment	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026