Role of antibiotic line locks in the prevention of tunnelled haemodialysis catheter infection: a double blind randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN93619348

Enrollment

Registered

2007-09-28

Start date

2006-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning: Haemodialysis catheter infection Injury, Occupational Diseases, Poisoning Complications of cardiac and vascular prosthetic devices, implants and grafts

Interventions

1G of vancomycin intraveously before catheter insertion. The catheter site will be inspected at each dialysis and cleaned with 10% aqueous povidone-iodine solution after each dialysis and each time th

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 and above, stratified according to their diabetic status, requiring the insertion of a new tunnelled haemodyalisis catheter.

Exclusion criteria

Exclusion criteria: 1. Antibiotics for longer than 2 weeks 2. Pregnancy or planned pregnancy 3. Pregnancy 4. Allergy to vancomycin or gemtamicin 5. History of heparin induced thrombocytopaenia

Design outcomes

Primary

Measure	Time frame
Time in days to catheter-related infections.	—

Secondary

Measure	Time frame
1. Haemoglobin concentration 2. Erythropoetin dose 3. Serum albumin concentration 4. Hospital admission rate 5. Mean length of hospital stay	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026