Nutritional, Metabolic, Endocrine: Hypopituitarism Nutritional, Metabolic, Endocrine Hypopituitarism
Conditions
Interventions
The study will be of randomised, open-label, crossover design, comparing the effects of traditional glucocorticoid replacement regimens versus modern regimens on fibrinolytic parameters in patients wi
Sponsors
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Eligibility
Inclusion criteria
Inclusion criteria: All patients over 18 years with documented adult hypopituitarism with proven ACTH deficiency, currently under follow up in the Bradford Teaching Hospitals NHS Trust, who have provided informed consent will be potentially eligible to participate in the study. Patients will be recruited from either direct contact in OPD or via direct phone contact with an endocrine specialist nurse.
Exclusion criteria
Exclusion criteria: 1. Subjects requiring systematic steroid therapy 2. Subjects taking HRT or oral contraceptive 3. Subjects who are currently pregnant or who had recent pregnancy or abortion 4. Subjects with known malignancy 5. Subjects with known coagulopathy 6. Subjects who are currently taking or have recently taken anticoagulant therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibrinolytic parameter measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed