The effect of airway pressure release ventilation on respiration and circulation in post-operative heart surgery patients

The effect of airway pressure release ventilation (APRV) on the incidence of postoperative pulmonary complications in patients with cardiothoracic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN92666776

Enrollment

Registered

2020-02-10

Start date

2018-12-26

Completion date

Unknown

Last updated

2023-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications and cardiovascular complications Respiratory

Interventions

Patients who receive cardiothoracic surgery and need invasive mechanical ventilation after admission to the ICU are randomly divided into routine ventilation group (PCV group) and APRV group. The rand

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age above 18 2.Received cardiothoracic surgery and needed invasive mechanical ventilation after admission to the ICU

Exclusion criteria

Exclusion criteria: 1. Chronic obstructive pulmonary disease 2. Asthma 3. Mechanical ventilation pre-operation 4. Mechanical device to maintain hemodynamics

Design outcomes

Primary

Measure	Time frame
Electrical impedance imaging (EIT) was used to determine the difference in pulmonary gas distribution in patients undergoing cardiothoracic surgery before and after admission to the ICU after APRV	—

Secondary

Measure	Time frame
From patient records: 1. Incidence of ventilator-associated pneumonia 2. Incidence of atelectasis 3. Duration of mechanical ventilation 4. Length of ICU stay 5. Final outcome (death/survival)	—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026