The evaluation of a 12-week partially supervised, self-regulated exercise intervention in patients with cystic fibrosis

An evaluation of the efficacy of a 12-week partially supervised, self-regulated exercise intervention on physiological and psychometric indices in patients with cystic fibrosis: a randomized-controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN92573472

Enrollment

Registered

2020-02-24

Start date

2020-01-07

Completion date

Unknown

Last updated

2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis Nutritional, Metabolic, Endocrine Cystic Fibrosis

Interventions

Participants will make two visits, separated by 7 days, to the testing site (DCU) at baseline and post-intervention for a series of physiological and psychometric assessments. Participants will wear a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Established diagnosis of cystic fibrosis (positive sweat chloride or genetic identification test) 2. Residing in the Republic of Ireland 3. = 18 years of age 4. Lung function scores of = 50% predicted 5. Must not have undergone lung transplantation

Exclusion criteria

Exclusion criteria: 1. Undergone lung transplantation 2. Culturing MRSA, NTM or Burkholderia Cepacia

Design outcomes

Primary

Measure	Time frame
Cardiorespiratory fitness measured using cardiopulmonary exercise test with monitoring of ventilatory gases, heart rate (ECG), blood pressure and oxygen saturation at baseline and 12 weeks	—

Secondary

Measure	Time frame
1. Anthropometry measured using a stadiometer, electronic scales, bioelectrical impedance and waist-to-hip ratio conducted using tape-measurements at baseline and 12 weeks 2. Muscle strength measured using sit-to-stand and biodex isokinetic dynamometry for lower extremity strength and hand-grip dynamometry for upper body strength at baseline and 12 weeks 3. Pulmonary function assessed using spirometry (EasyOne Air device) at baseline and 12 weeks 4. Physical activity assessed using accelerometry (ActivPAL) at baseline and 12 weeks 5. Quality of life evaluated using a CF-specific questionnaire (CFQ-R) at baseline and 12 weeks	—

Measure

Time frame

1. Anthropometry measured using a stadiometer, electronic scales, bioelectrical impedance and waist-to-hip ratio conducted using tape-measurements at baseline and 12 weeks 2. Muscle strength measured using sit-to-stand and biodex isokinetic dynamometry for lower extremity strength and hand-grip dynamometry for upper body strength at baseline and 12 weeks 3. Pulmonary function assessed using spirometry (EasyOne Air device) at baseline and 12 weeks 4. Physical activity assessed using accelerometry (ActivPAL) at baseline and 12 weeks 5. Quality of life evaluated using a CF-specific questionnaire (CFQ-R) at baseline and 12 weeks

—

Countries

Ireland

Contacts

Public ContactNicola Hurley

nicola.hurley5@mail.dcu.ie+353 017008470

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026