Exploring the effects of different types of therapeutic exercises in older people with sarcopenia (loss of muscle mass and strength)

The relationship between therapeutic exercise and parameters of quality of life in patients with sarcopenia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN92538100

Enrollment

Registered

2018-05-16

Start date

2017-03-14

Completion date

Unknown

Last updated

2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia Musculoskeletal Diseases Sarcopenia

Interventions

Participants are randomized into three groups – Group A, Group B and Group C Group A: Participants receive supervised group therapeutic exercises two times per week for 12 weeks. Furth

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Sarcopenic patients according the European Working Group on Sarcopenia in Older People criteria (EWGSOP) 2. Aged 60 years and older 3. Not currently engaged in exercise training (within last 3 months)

Exclusion criteria

Exclusion criteria: 1. Cognitive impairments 2. Neurological disorders 3. Pacemaker fitted 4. Cardiovascular diseases or high blood pressure not controlled with medication 5. Surgery on lower limbs affecting gait 6. Medical or other musculoskeletal problems that could affect ability to complete objective assessments, or exercise with safety 7. Currently engaged in exercise training (within last 3 months)

Design outcomes

Primary

Measure	Time frame
1. Quality of life is assessed using the Sarcopenia Quality of Life (SarQol) questionnaire at baseline, 12 weeks, 24 weeks and 12 months 2. Muscle strength is assessed with Biodex isokinetic dynamometer for knee flexors and extensors at baseline, 12 weeks and 24 weeks 3. Gait speed is assessed using the 4-m test at baseline, 12 weeks and 24 weeks	—

Secondary

Measure	Time frame
1. Function is assessed using the Timed Up and Go Test and sit to stand test (5 repetitions) at baseline, 12 weeks and 24 weeks 2. Fatigue is assessed using the FSS questionnaire at baseline, 12 weeks, 24 weeks and 12 months 3. Fear of falling is assessed using the FES questionnaire at baseline, 12 weeks, 24 weeks and 12 months 4. Body composition and Muscle mass is assessed using Bioelectrical impedance analysis (Tanita BC 601) at baseline, 12 weeks and 24 weeks 5. Calf measurement is assessed in cm at baseline, 12 weeks and 24 weeks 6. Depression and anxiety is assessed using the HADS questionnaire at baseline, 12 weeks and 24 weeks 7. Hand grip muscle strength is assessed with handheld grip dynamometer (SAEHAN) at baseline, 12 weeks and 24 weeks 8. Balance is assessed with the Berg Balance Scale at baseline, 12 weeks and 24 weeks 9. Nutrition is assessed with the SNAG questionnaire at baseline, 12 weeks, 24 weeks and 12 months post exercise 10. Physical activity is assessed with PASE questionnaire at baseline 11. Mental state is assessed with the Mini Mental Scale at baseline	—

Measure

Time frame

1. Function is assessed using the Timed Up and Go Test and sit to stand test (5 repetitions) at baseline, 12 weeks and 24 weeks 2. Fatigue is assessed using the FSS questionnaire at baseline, 12 weeks, 24 weeks and 12 months 3. Fear of falling is assessed using the FES questionnaire at baseline, 12 weeks, 24 weeks and 12 months 4. Body composition and Muscle mass is assessed using Bioelectrical impedance analysis (Tanita BC 601) at baseline, 12 weeks and 24 weeks 5. Calf measurement is assessed in cm at baseline, 12 weeks and 24 weeks 6. Depression and anxiety is assessed using the HADS questionnaire at baseline, 12 weeks and 24 weeks 7. Hand grip muscle strength is assessed with handheld grip dynamometer (SAEHAN) at baseline, 12 weeks and 24 weeks 8. Balance is assessed with the Berg Balance Scale at baseline, 12 weeks and 24 weeks 9. Nutrition is assessed with the SNAG questionnaire at baseline, 12 weeks, 24 weeks and 12 months post exercise 10. Physical activity is assessed with PASE questionnaire at baseline 11. Mental state is assessed with the Mini Mental Scale at baseline

—

Countries

Greece

Contacts

Public ContactMaria;John Tsekoura;Gliatis

;

mariatsekoura@hotmail.com;gliatis@hotmail.com+302691061150;2613603000

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026