A trial to investigate the role of the food supplement inositol in the general health of those at risk of developing gestational diabetes mellitus

A randomised controlled trial to investigate the role of myoinositol and D-chiro-inositol (in physiological ratio 40:1) in the general health of those at risk of developing gestational diabetes mellitus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN92466608

Enrollment

489

Registered

2013-10-31

Start date

2013-11-18

Completion date

Unknown

Last updated

2018-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes mellitus Pregnancy and Childbirth Diabetes mellitus arising in pregnancy

Interventions

Current interventions as of 09/04/2014: Participants will be randomized to one of the following two groups: 1. Intervention group. This group will take D-chiro-inositol (11.8 mg) and folic acid (400 m

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Any woman aged over 18 booking before 14 weeks with a first-degree relative who has diabetes

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancy 2. Known or suspected congenital abnormality 3. Any disease effecting the liver or pancreas

Design outcomes

Primary

Measure	Time frame
Development of gestational diabetes mellitus, measured at 26 weeks gestation	—

Secondary

Measure	Time frame
1. Mode of delivery of the baby 2. Birth weight 3. Incidence of maternal or newborn morbidities All of the above are recorded at delivery.	—

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026