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Will exposure to fire smoke at the Grenfell Tower fire cause long-term adverse health effects to firefighters of the London Fire Brigade?

The Grenfell Firefighters; establishing a cohort

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN92425651
Enrollment
1100
Registered
2019-05-31
Start date
2020-02-27
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory and cardiovascular disease

Interventions

No intervention. At the baseline survey we will make a series of non-invasive, physiological measurements of lung (spirometry and impulse oscillometry before and after a bronchodilator) and cardiac fu
largely though data linkage.

Sponsors

Imperial College, London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Firefighters who directly attended the Grenfell Tower fire in June 2017 2. A sample from those who were eligible to attend the fire but did not do so because of annual leave etc.

Exclusion criteria

Exclusion criteria: N/A

Design outcomes

Primary

MeasureTime frame
Airway resistance at 5Hz is measured using impulse oscillometry at baseline survey.

Secondary

MeasureTime frame
1. Airway resistance and airflow are measured through impulse oscillometry and spirometry at baseline. 2. Arterial stiffness measured by Vicorder at baseline. 3. Respiratory symptoms are measured using a questionnaire at baseline. 4. The incidence of cardiorespiratory disease is measured using data linkage to national and other registers at any point in the future 5. The incidence of cancers is measured using data linkage to national and other registers at any point in the future.

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026