Stroke Nervous System Diseases Stroke
Conditions
Interventions
Current interventions as of 07/09/2017:
22 patients who have had their first-ever stroke, affecting initially their right hand function and 22 age-matched controls attend four study vi
Sponsors
University of East London
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 07/09/2017: Patients: 1. Adults over 18 years old 2. Stroke affecting arm function 3. Right handed before the stroke 4. With no neurological history before the stroke 5. Recovered 6 months after stroke or earlier 6. With no history of seizures post-stroke 7. With good command of English Controls: 1. Participants matched with patients by age 2. Adults over 18 years old 3. Right handed 4. With no neurological history 5. With good command of English Previous inclusion criteria: Patients: 1. Adults over 18 years old 2. Left middle cerebral artery stroke 3. Stroke affecting arm function 4. Right handed before the stroke 5. With no neurological history before the stroke 6. Recovered 6 months after stroke or earlier 7. With no history of seizures post-stroke 8. With good command of English Controls: 1. Participants matched with patients by age and socioeconomic status, preferably from their close social circle 2. Adults over 18 years old 3. Right handed 4. With no neurological history 5. With good command of English
Exclusion criteria
Exclusion criteria: Patients: 1. Neurological disorders that could influence the EEG data recording 2. Left-handedness before stroke 3. No recovery of arm function 6 months after stroke 4. Inability to be assessed due to not sufficient command of English Controls: 1. History of neurological disorders that could influence the EEG data recording 2. Left-handedness 3. Inability to be assessed due to not sufficient command of English
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measures: Neural correlates of motor adaptation are measured using EEG recording during the motor adaptation task on the third study visit. Previous primary outcome measures: Neural correlates of motor adaptation are measured using EEG recording during the motor adaptation task on the fourth study visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 07/09/2017: 1. Motor adaptation is measured using robot's kinematic recording during the motor adaptation task on the third study visit 2. Motor adaptation is measured using EMG recording during the motor adaptation task on the third study visit 3. Motor function is measured using : 3.1. The robot-mediated evaluation test on the third study visit 3.2. A dynamometer on the third study visit 3.3. A pinchmeter on the third study visit 3.4. The Fugl-Meyer assessment on the first and second study visit 4. Verbal learning is measured by CVLT on the second study visit 5. Lesion size is measured using a clinical MRI scan, if available and this measure doeas not involve any additional study visits Screening measures: 1. Fatigue is screened using the Oxford Cognitive Screen on the second study visit 2. Aphasia is screened using the Oxford Cognitive Screen on the second study visit 3. Visual neglect is screened using the Bells test on the second study visit Previous secondary outcome measures: 1. Motor adaptation is measured using robot's kinematic recording during the motor adaptation task on the fourth study visit 2. Motor adaptation is measured using EMG recording during the motor adaptation task on the fourth study visit 3. Motor function is measured using : 3.1. The robot-mediated evaluation test on the fourth study visit 3.2. A dynamometer on the fourth study visit 3.3. A pinchmeter on the fourth study visit 3.4. The Fugl-Meyer assessment on the first and third study visit 3.5. The DASH assessment on the first and second study visit 4. Verbal learning is measured by C | — |
Countries
United Kingdom
Contacts
Public ContactAdela Desowska
Outcome results
None listed