FindTrial
Sign In

A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN92341395
Enrollment
Unknown
Registered
2002-08-19
Start date
2000-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer Cancer Colorectal cancer

Interventions

1. Arm A: Surgery without transfusion 2. Arm B: Surgery with standard blood transfusion 3. Arm C: Surgery with leucodepleted blood transfusion

Sponsors

Leicester General Hospital (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective resection of colorectal carcinoma 2. No transfusion of blood in the 6 months preceding the operation 3. No transfusion of blood prior to the first postoperative sample 4. No concurrent immunosuppressive medication 5. No previous transfusion reaction requiring cessation of transfusion

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026