Acute coronary syndrome Circulatory System Acute coronary syndrome
Conditions
Interventions
Point-Of-Care testing in the emergency department vs central hospital laboratory testing for troponin I measurement.
Sponsors
Dade Behring (France)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18 years or older 2. Suspicion of acute coronary syndrom 3. Required to measure troponin I (Ti)
Exclusion criteria
Exclusion criteria: 1. Patients presenting with ST-elevation Acute Coronary Syndrome (ACS) (typical chest pain and persistent [>20 min] ST-segment elevation [>0.1 mV in limb leads or 0.2 mV in precordial leads]) did not represent such a diagnostic challenge compared to NSTE-ACS and were candidate for urgent reperfusion procedure, and therefore were excluded from the current analysis. Other exclusion criteria: 2. Refusal or inability to provide informed consent 3. Previous enrolment in the study Additionally, aiming to select patients with high risk ACS, the patients who had 1-2 Ti levels consistently <0.10 µg/L within eight hours of the onset of ACS symptoms were excluded from the study post-hoc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to anti-ischemic therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to physician notification of troponin I level 2. Length of stay within the emergency department defined by the time to bed assignment 3. Mortality at 30 and 90 days after presentation 4. Level of emergency department staff reliability on Point-Of-Care testing versus central hospital laboratory testing as assessed by the proportion of second troponin I tests ordered after the Point-Of-Care testing | — |
Countries
France
Outcome results
None listed