Postnatal mental health / mother-infant attachment Pregnancy and Childbirth Postnatal depression
Conditions
Interventions
Intranasal administration of 24IU Syntocinon® (oxytocin) versus Intranasal administration of placebo (0.9% sodium chloride solution)
Video will be recorded of the mother-infant interaction following
Sponsors
NHS Greater Glasgow & Clyde (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Mother with history of low mood (recorded Edinburgh Postnatal Depression Score of ten or greater) with baby aged 8-16 weeks 2. Mother aged 18 ? 50 years
Exclusion criteria
Exclusion criteria: 1. Baby born before 38 weeks 2. Significant obstetric complications 3. Significant medical condition of mother or baby 4. Substantial neurological or visual impairment of mother or baby 5. Mother non-English speaking 6. Mother continuing to breast feed 7. Mother has physical condition which might affect nasal drug absorption (eg. URTI) 8. Mother responsible for care of another child at time of home visit 9. Mother pregnant 10. Mothers on antidepressant medication will not be excluded from the study; however we will record if a subject is on medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of mutual eye region gaze between mother and baby | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. CARE index will be calculated from the video footage (ie. at 45mins post-spray administration on both occasions) 2. Neonatal perception index will be completed at 0 and 45 minutes each time | — |
Countries
United Kingdom
Outcome results
None listed